Theralink is a Next-Generation Proteomics (NGPᵀᴹ) company. What does this even mean????
Well first, let’s bake a cake!
Step 1: Find a recipe
Step 2: Gather the ingredients
Step 3: Make the batter
Step 4: Bake in the Oven
Every one of these steps is necessary to get us our perfect and delicious dessert. The recipe is necessary so that we know what ingredients we need for the cake. We cannot make the batter without flour, eggs, and milk. We certainly cannot eat the raw batter- Salmonella is not cool. In order to match our cake to the picture, we need to make it all the way to the final step.
Similarly, in order to fully paint a picture of what is going on in the tumor microenvironment, we need to go all the way to the final step.
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The study of an organism’s complete set of DNA including all the genes (the genome) is called Genomics. The DNA forms the foundation for cellular and bodily function- but this is only the recipe. We can increase the amount of each ingredient to make more batter depending on how big of a cake we want. Comparably, RNA and transcriptomics come in with the ingredients to determine how much protein actually gets synthesized- but even this is still just the batter. Until we put the batter in the oven and “activate” the ingredients, we still don’t have a cake. This is where Next-Generation Proteomics (NGPᵀᴹ) comes in.
Proteomics is the study of all of the proteins (the proteome) synthesized, and/or modified by an organism. Using a combination of Laser Capture Microdissection (LCM) and patented Reverse Phase Protein Array (RPPA) technology, Theralink Technologies Inc., has the ability to go one step further. We quantify the activated proteome giving a clear picture of the key players in the tumor microenvironment and their activations states. For more information, contact Theralink for a quick overview of our general capabilities and translatability.